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1

The yeastKluyveromyces marxianusand its biotechnological potential

Gustavo Graciano Fonseca, Elmar Heinzle, Christoph Wittmann, Andreas K. Gombert

Journal:

Applied Microbiology and Biotechnology

Year:

2008

Language:

english

File:

PDF, 339 KB

english, 2008

2

MALDI-TOF MS for quantification of substrates and products in cultivations of Corynebacterium glutamicum

Christoph Wittmann, Elmar Heinzle

Journal:

Biotechnology and Bioengineering

Year:

2001

Language:

english

File:

PDF, 192 KB

english, 2001

3

Integrated optical sensing of dissolved oxygen in microtiter plates: A novel tool for microbial cultivation

Gernot T. John, Ingo Klimant, Christoph Wittmann, Elmar Heinzle

Journal:

Biotechnology and Bioengineering

Year:

2003

Language:

english

File:

PDF, 132 KB

english, 2003

4

In vivo quantification of intracellular amino acids and intermediates of the methionine pathway in Corynebacterium glutamicum

Jens Olaf Krömer, Michel Fritz, Elmar Heinzle, Christoph Wittmann

Journal:

Analytical Biochemistry

Year:

2005

Language:

english

File:

PDF, 204 KB

english, 2005

5

Metabolic network analysis of lysine producing Corynebacterium glutamicum at a miniaturized scale

Christoph Wittmann, Hyung Min Kim, Elmar Heinzle

Journal:

Biotechnology and Bioengineering

Year:

2004

Language:

english

File:

PDF, 119 KB

english, 2004

6

Impact of the cold shock phenomenon on quantification of intracellular metabolites in bacteria

Christoph Wittmann, Jens O Krömer, Patrick Kiefer, Tina Binz, Elmar Heinzle

Journal:

Analytical Biochemistry

Year:

2004

Language:

english

File:

PDF, 222 KB

english, 2004

7

Metabolic physiology of Pseudomonas putida for heterologous production of myxochromide

Sara Stephan, Elmar Heinzle, Silke C. Wenzel, Daniel Krug, Rolf Müller, Christoph Wittmann

Journal:

Process Biochemistry

Year:

2006

Language:

english

File:

PDF, 252 KB

english, 2006

8

In vivo analysis of intracellular amino acid labelings by GC/MS

Christoph Wittmann, Michael Hans, Elmar Heinzle

Journal:

Analytical Biochemistry

Year:

2002

Language:

english

File:

PDF, 80 KB

english, 2002

9

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for metabolic flux analyses using isotope-labeled ethanol

Klaus Hollemeyer, Vidya R. Velagapudi, Christoph Wittmann, Elmar Heinzle

Journal:

Rapid Communications in Mass Spectrometry

Year:

2007

Language:

english

File:

PDF, 167 KB

english, 2007

10

Enhancing mobile applications by combination of GNSS and W-CDMA

Guenter Heinrichs, Erwin Loehnert, Elmar Wittmann, Bernd Eissfeller

Journal:

Year:

2002

Language:

english

File:

PDF, 1.05 MB

english, 2002

11

[IEEE European Workshop on GNSS Signals and Signal Processing - Netherlands (2010.12.8-2010.12.10)] 2010 5th ESA Workshop on Satellite Navigation Technologies and European Workshop on GNSS Signals and Signal Processing (NAVITEC) - User RAIM integrity and interference mitigation test results with upgraded German Galileo test range GATE

Heinrichs, Guenter, Loehnert, Erwin, Wittmann, Elmar

Year:

2010

Language:

english

File:

PDF, 1.92 MB

english, 2010

12

Metabolic pathway analysis for rational design of L-methionine production by Escherichia coli and Corynebacterium glutamicum

Jens Olaf Krömer, Christoph Wittmann, Hartwig Schröder, Elmar Heinzle

Journal:

Metabolic Engineering

Year:

2006

Language:

english

File:

PDF, 827 KB

english, 2006

13

Respirometric 13C flux analysis, Part I: Design, construction and validation of a novel multiple reactor system using on-line membrane inlet mass spectrometry

Tae Hoon Yang, Christoph Wittmann, Elmar Heinzle

Journal:

Metabolic Engineering

Year:

2006

Language:

english

File:

PDF, 723 KB

english, 2006

14

Characterization and application of an optical sensor for quantification of dissolved O2in shake-flasks

Christoph Wittmann, Hyung Min Kim, Gernot John, Elmar Heinzle

Journal:

Biotechnology Letters

Year:

2003

Language:

english

File:

PDF, 76 KB

english, 2003

15

Respirometric 13C flux analysis—Part II: In vivo flux estimation of lysine-producing Corynebacterium glutamicum

Tae Hoon Yang, Christoph Wittmann, Elmar Heinzle

Journal:

Metabolic Engineering

Year:

2006

Language:

english

File:

PDF, 669 KB

english, 2006

16

Purification and characterization of full-length mammalian poly(A) polymerase

Torsten Wittmann, Elmar Wahle

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1997

Language:

english

File:

PDF, 1.26 MB

english, 1997

17

Dynamic calibration and dissolved gas analysis using membrane inlet mass spectrometry for the quantification of cell respiration

Tae Hoon Yang, Christoph Wittmann, Elmar Heinzle

Journal:

Rapid Communications in Mass Spectrometry

Year:

2003

Language:

english

File:

PDF, 220 KB

english, 2003

18

Physiology of the yeast Kluyveromyces marxianus during batch and chemostat cultures with glucose as the sole carbon source

Gustavo Graciano Fonseca, Andreas Karoly Gombert, Elmar Heinzle, Christoph Wittmann

Journal:

FEMS Yeast Research

Year:

2007

Language:

english

File:

PDF, 210 KB

english, 2007

19

Microplates with integrated oxygen sensing for medium optimization in animal cell culture

Rahul Ravi Deshpande, Chistoph Wittmann, Elmar Heinzle

Journal:

Year:

2004

Language:

english

File:

PDF, 360 KB

english, 2004

20

Metabolic network simulation using logical loop algorithm and Jacobian matrix

Tae Hoon Yang, Christoph Wittmann, Elmar Heinzle

Journal:

Metabolic Engineering

Year:

2004

Language:

english

File:

PDF, 501 KB

english, 2004

21

Metabolite profiling studies inSaccharomyces cerevisiae: an assisting tool to prioritize host targets for antiviral drug screening

Konstantin Schneider, Jens Olaf Krömer, Christoph Wittmann, Isabel Alves-Rodrigues, Andreas Meyerhans, Juana Diez, Elmar Heinzle

Journal:

Microbial Cell Factories

Year:

2009

Language:

english

File:

PDF, 1.07 MB

english, 2009

22

Mass spectrometry for metabolic flux analysis

Christoph Wittmann, Elmar Heinzle

Journal:

Biotechnology and Bioengineering

Year:

1999

Language:

english

File:

PDF, 201 KB

english, 1999

23

Theoretical aspects of 13C metabolic flux analysis with sole quantification of carbon dioxide labeling

Tae Hoon Yang, Elmar Heinzle, Christoph Wittmann

Journal:

Computational Biology and Chemistry

Year:

2005

Language:

english

File:

PDF, 602 KB

english, 2005

24

Application of MALDI-TOF MS to lysine-producing Corynebacterium glutamicum : A novel approach for metabolic flux analysis

Christoph Wittmann, Elmar Heinzle

Journal:

Year:

2001

Language:

english

File:

PDF, 1.26 MB

english, 2001

25

Interconversion and Kinetic Properties of Pyruvate Dehydrogenase from Brain

SIESS, ELMAR, WITTMANN, JOSEF, WIELAND, OTTO

Journal:

Hoppe-Seyler's Zeitschrift für physiologische Chemie

Year:

1971

Language:

english

File:

PDF, 919 KB

english, 1971

26

Quantification ofS-adenosyl Methionine in Microbial Cell Extracts

Jens Olaf Krömer, Elmar Heinzle, Christoph Wittmann

Journal:

Biotechnology Letters

Year:

2006

Language:

english

File:

PDF, 187 KB

english, 2006

27

Correcting mass isotopomer distributions for naturally occurring isotopes

Wouter A. Van Winden, Christoph Wittmann, Elmar Heinzle, Joseph J. Heijnen

Journal:

Biotechnology and Bioengineering

Year:

2002

Language:

english

File:

PDF, 65 KB

english, 2002

28

Free intracellular amino acid pools during autonomous oscillations in Saccharomyces cerevisiae

Michael A. Hans, Elmar Heinzle, Christoph Wittmann

Journal:

Biotechnology and Bioengineering

Year:

2003

Language:

english

File:

PDF, 163 KB

english, 2003

29

Analysis of 13C labeling enrichment in microbial culture applying metabolic tracer experiments using gas chromatography–combustion–isotope ratio mass spectrometry

Elmar Heinzle, Yongbo Yuan, Sathish Kumar, Christoph Wittmann, Matthias Gehre, Hans-Herrmann Richnow, Patrick Wehrung, Pierre Adam, Pierre Albrecht

Journal:

Analytical Biochemistry

Year:

2008

Language:

english

File:

PDF, 451 KB

english, 2008

30

Metabolic screening of Saccharomyces cerevisiae single knockout strains reveals unexpected mobilization of metabolic potential

Vidya R. Velagapudi, Christoph Wittmann, Thomas Lengauer, Priti Talwar, Elmar Heinzle

Journal:

Process Biochemistry

Year:

2006

Language:

english

File:

PDF, 453 KB

english, 2006

31

Derivatization of small biomolecules for optimized matrix-assisted laser desorption/ionization mass spectrometry

Andreas Tholey, Christoph Wittmann, Min-Jung Kang, Ditte Bungert, Klaus Hollemeyer, Elmar Heinzle

Journal:

Journal of Mass Spectrometry

Year:

2002

Language:

english

File:

PDF, 167 KB

english, 2002

32

Modeling and Experimental Design for Metabolic Flux Analysis of Lysine-Producing Corynebacteria by Mass Spectrometry

Christoph Wittmann, Elmar Heinzle

Journal:

Metabolic Engineering

Year:

2001

Language:

english

File:

PDF, 468 KB

english, 2001

33

Metabolic flux screening of Saccharomyces cerevisiae single knockout strains on glucose and galactose supports elucidation of gene function

Vidya R. Velagapudi, Christoph Wittmann, Konstantin Schneider, Elmar Heinzle

Journal:

Journal of Biotechnology

Year:

2007

Language:

english

File:

PDF, 696 KB

english, 2007

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